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Study Name
Condition investigated
Location
Clinical, Neurocognitive, and Emotional Effects of Psilocybin in Depressed Patients - Proof of Concept
Depression
Switzerland
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Ketamine Versus Electroconvulsive Therapy in Depression
Depression
Canada
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MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function
Healthy
United States
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Direct Comparison of Altered States of Consciousness Induced by LSD and Psilocybin
Healthy
Basel
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Psilocybin - Induced Neuroplasticity in the Treatment of Major Depressive Disorder
Depression
United States
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Effect of Methylenedioxymethamphetamine (MDMA) (Serotonin Release) on Fear Extinction
Healthy
Switzerland
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Intranasal Ketamine With Dexmedetomidine for the Treatment of Children With Autism Spectrum Disorder
Autism
China
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NRX100 vs. Placebo for Rapid Stabilization of Acute Suicidal Ideation and Behavior in Bipolar Depression
Suicidal Ideation
United States
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Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response
Depression
United States
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Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study.
OCD
United States
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ECT With Ketamine Anesthesia vs High Intensity Ketamine With ECT Rescue for Treatment-Resistant Depression
Depression
Canada
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Intravenous Ketamine Plus Neurocognitive Training for Depression
Depression
United States
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Evaluation of MDMA on Startle Response
Healthy
United States
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LSD Treatment in Persons Suffering From Anxiety Symptoms in Severe Somatic Diseases or in Psychiatric Anxiety Disorders
Anxiety
Switzerland
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Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder
Depression
United States
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Investigation of Antidepressant Efficacy of Oral Ketamine Treatment
Depression
Austria
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Psilocybin for the Treatment of Cluster Headache
Cluster Headache
United States
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Evaluation of the Initial Prescription of Ketamine and Milnacipran for Depression in Palliative Care
Depression
France
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Positron Emission Tomography Assessment of Ketamine Binding of the Serotonin Transporter
Depression
Austria
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Understanding How Ketamine Brings About Rapid Improvement in OCD
OCD
United States
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Neurobiology of Suicide
Suicidal Ideation
United States
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Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder
Depression
United States
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miRNAs, Suicide, and Ketamine - Plasma Exosomal microRNAs as Novel Biomarkers for Suicidality and Treatment Outcome
Depression
United States
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Effects of Psilocybin-facilitated Experience on the Psychology and Effectiveness of Professional Leaders in Religion
Healthy
United States
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Ketamine Alcohol (in Treatment-Resistant Depression)
Depression
United States
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The Effect of Ketamine on Mechanises Underlying Suicidal Ideation and Drug-resistant Major Depression
Suicidal Ideation
Israel
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Psilocybin-facilitated Smoking Cessation Treatment: A Pilot Study
Nicotine Dependence
United States
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Psilocybin as a Treatment for Anorexia Nervosa: A Pilot Study
Eating Disorder
United Kingdom
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Ketamine for Older Adults Pilot
Depression
North America
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Precision Functional Brain Mapping in Psilocybin
Healthy
United States
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University of Iowa Interventional Psychiatry Service Patient Registry
Depression
United States
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Ketamine or Placebo in Patients With Major Depression and Advanced Cancer
Depression
Mexico
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A Multi-site Study of MDMA-Assisted Psychotherapy for Eating Disorders
Eating Disorder
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An Open Label Study of the Safety and Efficacy of Psilocybin in Participants With Treatment-Resistant Depression (P-TRD)
Depression
United States
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The Safety and Efficacy of Psilocybin in Participants With Type 2 Bipolar Disorder (BP-II) Depression.
Depression
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Visual Surround Suppression and Perceptual Expectation Under Psilocybin
United States
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Low-dose S-ketamine in Women With Prenatal Depression
Prenatal depression
China
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Pilot Trial of Visual Healing® in Psilocybin-assisted Therapy for Alcohol Use Disorder
Alcohol Use Disorder
United States
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The Effect of S-ketamine for Patients Undergoing Electroconvulsive Therapy (ECT)
Depression
China
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Effects of Dimethyltryptamine in Healthy Subjects
Healthy
Switzerland
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Study to Assess the Effects of Intranasal Ketamine Along With rTMS for Patients With Treatment-resistant Major Depressive Disorder (TRD)
Depression
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A Study of Different Oral Thin Film (S)-Ketamine Formulations for Sublingual Administration in Healthy Participants
Healthy
Belgium
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A Study of Sublingually Administered (S)-Ketamine Oral Solution in Healthy Participants
Healthy
Belgium
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Prophylactic Effects of Psilocybin on Chronic Cluster Headache
Cluster Headache
Denmark
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MDMA-Assisted Psychotherapy in Veterans With Combat-Related, Refractory PTSD
PTSD (Post Traumatic Stress Disorder)
United States
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Comparative Acute Effects of LSD, Psilocybin and Mescaline
Healthy
Switzerland
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Ketamine to Prevent PPD After Cesarean
Postpartum Depression
United States
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A Naturalistic Study of Ketamine for Treatment Resistant Mood Disorders
Depression
Poland
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Repeat Dosing of Psilocybin in Migraine Headache
Migraine Headache
United States
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Biomarkers of Response to Ketamine in Depression: MRI and Blood Assays Before and After Open Label Intranasal Ketamine
Depression
United States
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Effect of Ketamine Intranasal Spray in Treatment of Chronic Cluster Headache
Cluster Headache
Denmark
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Ketamine for the Treatment of Opioid Use Disorder and Depression
Depression
United States
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Adjunctive Effects of Psilocybin and Buprenorphine
Opioid Use Disorder
United States
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Clinical and Mechanistic Effects of Psilocybin in Alcohol Addicted Patients
Alcohol Use Disorder
Switzerland
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Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease
Depression
United States
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A Study of HR071603(Ketamine Nasal Spray) in Healthy Subjects
Depression
China
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A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP2)
PTSD (Post Traumatic Stress Disorder)
Worldwide
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Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-2)
Healthy
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Stanford Reward Circuits of the Brain Study - MDMA
Healthy
United States
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Effects of Drugs on Responses to Brain and Emotional Processes
Autism
United States
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Effects of Psilocybin in Anorexia Nervosa
Eating Disorder
United States
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Psychedelics and Wellness Study (PAWS)
United States
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Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD With Optional fMRI Sub-Study
PTSD (Post Traumatic Stress Disorder)
Europe
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Ketamine for Treatment Resistant MDD
Depression
Israel
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The Role of HNKs in the Antidepressant Effect of Ketamine
Depression
United States
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Mechanism of Action Underlying Ketamine s Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression
Depression
United States
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Ketamine and Prolonged Exposure in PTSD
PTSD
United States
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Ketamine Infusion Therapy for the Treatment of PTSD in Paramedics
PTSD
United States
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Low-dose S-Ketamine and Postpartum Depression in Parturients With Prenatal Depression
Depression
China
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LSD Therapy for Persons Suffering From Major Depression
Depression
Switzerland
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A Study of Psilocybin for Major Depressive Disorder (MDD)
Depression
United States
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Effect of Stimulant Drugs on Social Perception
Healthy
United States
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Intranasal Ketamine for Suicidal Ideation in Veterans
Suicidal Ideation
United States
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Lysergic Acid Diethylamide (LSD) as Treatment for Cluster Headache
Cluster Headache
Switzerland
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The Safety and Efficacy of Psilocybin in Participants With Treatment Resistant Depression
Depression
Everywhere
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The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD.
PTSD
United States
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Evaluation of Schemes of Administration of Intravenous Ketamine in Depression
Depression
Mexico
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Evaluation of MDMA on Startle Response
Healthy
Georgia, USA
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A Double-Blind Trial of Psilocybin-Assisted Treatment of Alcohol Dependence
Alcohol Dependence
New York | New Mexico, USA
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A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP1)
PTSD
USA | Canada | Israel
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A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD II
PTSD
USA | Canada | Israel
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A Study of Psilocybin for Major Depressive Disorder (MDD)
Depression
San Francisco, USA
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Adjunctive Effects of Psilocybin and Buprenorphine
Opioid Use
Wisconsin, USA
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Bristol Imperial MDMA in Alcoholism Study
Alcohol Dependence
Bristol, UK
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Clinical and Mechanistic Effects of Psilocybin in Alcohol Addicted Patients
Alcohol Dependence
Zurich, Switzerland
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Clinical, Neurocognitive, and Emotional Effects of Psilocybin in Depressed Patients - Proof of Concept
Depression
Zurich, Switzerland
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Direct Comparison of Altered States of Consciousness Induced by LSD and Psilocybin
Healthy
Basel, Switzerland
find out more
Effect of Methylenedioxymethamphetamine (MDMA) (Serotonin Release) on Fear Extinction
Healthy
Basel, Switzerland
Effect of Stimulant Drugs on Social Perception
Healthy
Chicago, USA
Effects of Drugs on Responses to Brain and Emotional Processes
Autism
Chicago, USA
Effects of Psilocybin in Anorexia Nervosa
Anorexia
Baltimore, USA
Effects of Psilocybin in Major Depressive Disorder
Depression
Baltimore, USA
Effects of Psilocybin in Post-Traumatic Headache
Headache
Connecticut, USA
Effects of Psilocybin-facilitated Experience on the Psychology and Effectiveness of Professional Leaders in Religion
Healthy
Baltimore, USA
Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study.
OCD
Connecticut, USA
Ketamine Infusion Therapy for the Treatment of PTSD in Paramedics
PTSD
Texas, USA
LSD Therapy for Persons Suffering From Major Depression
Depression
Basel, Switzerland
LSD Treatment in Persons Suffering From Anxiety Symptoms in Severe Somatic Diseases or in Psychiatric Anxiety Disorders
Anxiety
Basel, Switzerland
Lysergic Acid Diethylamide (LSD) as Treatment for Cluster Headache
Healthy
Basel, Switzerland
MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function
Healthy / Liver Impairment
California, USA
Mood Effects of Serotonin Agonists
Healthy
Chicago, USA
Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD
PTSD
USA
Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD With Optional fMRI Sub-Study
PTSD
Europe
Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone Detoxification
Opioid Dependence
Reus, Spain
Psilocybin - Induced Neuroplasticity in the Treatment of Major Depressive Disorder
Depression
Connecticut, USA
Psilocybin and Depression
Depression
Europe
Psilocybin Cancer Anxiety Study
Cancer
New York, USA
Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease
Depression
Baltimore, USA
Psilocybin for the Treatment of Cluster Headache
Headache
Connecticut, USA
Psilocybin for the Treatment of Migraine Headache
Headache
Connecticut, USA
Psilocybin for Treatment of Obsessive Compulsive Disorder
OCD
Arizona, USA
Psilocybin vs Escitalopram for Major Depressive Disorder: Comparative Mechanisms
Depression
London, UK
Psilocybin-facilitated Smoking Cessation Treatment: A Pilot Study
Smokers
Baltimore, USA
Psilocybin-facilitated Treatment for Cocaine Use
Opioid Dependence
Alabama, USA
Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-2)
Healthy
Repeat Dosing of Psilocybin in Migraine Headache
Headache
Connecticut, USA
Stanford Reward Circuits of the Brain Study - MDMA
Healthy
Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD
PTSD
British Columbia | Quebec, Canada
The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD.
PTSD
Connecticut, USA
The Effects of Psilocybin-Facilitated Experience on the Psychology and Effectiveness of Religious Professionals
Religious
New York, USA
The Neurobiological Effect of 5-HT2AR Modulation
Healthy
Copenhagen, Denmark
The Safety and Efficacy of Psilocybin in Participants With Treatment Resistant Depression
Depression
Global
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